Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05327504

Written Exposure Therapy for Veterans With SUD and PTSD

Led by VA Office of Research and Development · Updated on 2026-02-19

170

Participants Needed

1

Research Sites

248 weeks

Total Duration

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AI-Summary

What this Trial Is About

The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD). While SUD treatment programs traditionally do not address PTSD, effective trauma treatments have been used successfully among those with substance use comorbidities. WET is a brief trauma-focused intervention shown to effectively treat PTSD. In a recent acceptability and feasibility pilot study among Veterans with co-occurring SUD and PTSD, results showed a decrease in PTSD symptoms among participants receiving WET. The goal of the present study is to improve outcomes for Veterans who present for SUD treatment with comorbid SUD/PTSD.

CONDITIONS

Official Title

Written Exposure Therapy for Veterans With SUD and PTSD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Veterans ages 18 years old or older
  • Meets DSM-5 criteria for at least one substance use disorder (SUD)
  • Meets DSM-5 criteria for PTSD
  • Approved for SUD treatment at VA Connecticut Healthcare System
Not Eligible

You will not qualify if you...

  • Current diagnosis of schizophrenia, schizophrenia-type disorders, or unmedicated mania or bipolar disorder as determined by QuickSCID-5
  • Current suicidal or homicidal risks requiring higher level care
  • Received evidence-based psychotherapy for PTSD within the past 6 months
  • Problems preventing completion of writing intervention or study assessments (e.g., illiteracy)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Connecticut Healthcare System West Haven Campus, West Haven, CT

West Haven, Connecticut, United States, 06516-2770

Actively Recruiting

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Research Team

V

Vera Bici, BA

CONTACT

A

Amanda O'Brien, MA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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