Actively Recruiting

Phase Not Applicable
All Genders
NCT07167381

xDRIVE for Florida-based Cancer Patients

Led by First Ascent Biomedical Inc. · Updated on 2025-12-23

210

Participants Needed

2

Research Sites

73 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Through this study funded by the Florida Cancer Innovation Fund, First Ascent will demonstrate state-wide feasibility of providing xDRIVE Functional Precision Medicine + Artificial Intelligence platform by assessing patient clinical benefit and health economics impacts. As this is a feasibility study, results will be returned to the physician and the physician may use the data to inform the next line of treatment. The investigator will run a prospective single-arm feasibility study providing the xDRIVE FPM AI platform to n = 210+ cancer patients throughout the state of Florida, especially those from underserved populations (pediatric patients and patients in Black, Brown, Hispanic, and rural communities).

CONDITIONS

Official Title

xDRIVE for Florida-based Cancer Patients

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with recurrent or refractory cancer up to age 18 who are willing to sign assent if aged 7 to 17 years
  • Patients with recurrent or refractory cancer 18 years of age or older
  • Patients who have received at least one prior line of standard of care therapy
  • Patients able to provide treatment and outcome information from previous therapies
  • Patients with sufficient health to undergo cancer therapy, such as ECOG status 0, 1, or 2 for adults
  • Patients scheduled for or recently undergone a tumor biopsy, excision, or resection
  • Patients willing to have a blood draw or buccal swab for matched normal tissue during tumor DNA profiling
Not Eligible

You will not qualify if you...

  • Patients without available or accessible malignant tissue or with insufficient malignant tissue for testing (<0.3 g for resections or biopsies lacking malignant cells)
  • Patients with insufficient health indicators to undergo therapeutic intervention

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

First Ascent Biomedical

Miami, Florida, United States, 33183

Actively Recruiting

2

Florida International University

Miami, Florida, United States, 33199

Active, Not Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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