Actively Recruiting
Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial
Led by Amr Anwar Mohamed Ellithy Yousef · Updated on 2024-09-19
20
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Peri-implant soft tissue dehiscences are common problems in implant dentistry that cause challenges for both appearance and function. Researchers are comparing two treatments: Xengenic cortical membranes and connective tissue graft with coronally advanced flap, to find which is better for improving soft tissue around implants. This is a randomized, controlled clinical trial aimed at evaluating outcomes and patient experiences with these treatments. The trial involves two groups receiving different soft tissue surgeries around dental implant dehiscence. One group is treated with Xengenic cortical membranes, a device used to support tissue regeneration. The other group receives a connective tissue graft combined with a coronally advanced flap procedure. Both treatments are provided under controlled conditions as part of the study. Participants will be monitored over six months to assess changes in peri-implant soft tissue thickness, which is the main outcome measure. Researchers will also evaluate the pink esthetic score to understand the appearance improvements. Throughout the study, participants' compliance and oral hygiene will be tracked to support treatment success. The study duration includes regular visits and assessments for accurate measurement of the results.
CONDITIONS
Brief Title
Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 20 to 50 years
- Presence of peri-implant soft tissue dehiscence
- Thin gingival tissue type
- Willingness and ability to attend all treatment appointments
- Positive attitude and compliance with oral hygiene instructions
You will not qualify if you...
- Medically compromised patients or those with conditions preventing implant or periodontal surgery
- Smokers
- People with diabetes
- Pregnant or breastfeeding women
- History of chemotherapy or radiotherapy in the head or neck area
- Current or past use of bisphosphonate therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to a few days around surgery
Participants undergo soft tissue surgery around dental implant dehiscence using either Xengenic cortical membranes or connective tissue graft with coronally advanced flap.
1 surgery visit (in-person) and immediate recovery visits
Duration - 6 months
Participants are monitored for healing and outcomes related to the surgery, including soft tissue thickness and esthetic evaluation.
Approximately 6 post-operative visits
Trial Site Locations
Total: 1 location
1
TantaU
Tanta, Gharbia Governorate, Egypt
Actively Recruiting
Research Team
A
amr anwar ellithy, MSC
B
bassem nabil elfahl, PHD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here