Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
Healthy Volunteers
NCT02484885

Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility

Led by Western University, Canada · Updated on 2024-06-13

50

Participants Needed

1

Research Sites

730 weeks

Total Duration

On this page

Sponsors

W

Western University, Canada

Lead Sponsor

L

London Health Sciences Centre

Collaborating Sponsor

AI-Summary

What this Trial Is About

Healthy volunteers aged 18-85 will undergo hyperpolarized 129-Xe MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.

CONDITIONS

Official Title

Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility

Who Can Participate

Age: 18Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to hold breath for up to 16 seconds
  • Body mass index (BMI) between 18 and 40
  • Stable health based on medical history
  • Smoking history less than 1 pack per year
Not Eligible

You will not qualify if you...

  • Mentally or legally incapacitated, unable to provide informed consent or understand study materials
  • Daytime room air oxygen saturation less than 90% while lying down
  • Unable to perform spirometry or plethysmography tests
  • Pregnant
  • Conditions preventing MRI performance such as severe claustrophobia
  • Implanted mechanical, electrical, or magnetic devices or any metal in the body that cannot be removed, including pacemakers, neurostimulators, insulin pumps, aneurysm clips, artificial limbs, metallic fragments, shunts, surgical staples, or ear implants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre

London, Ontario, Canada, N6A 5B7

Actively Recruiting

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Research Team

G

Grace E Parraga, PhD

CONTACT

A

Angela P Wilson, RRT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility | DecenTrialz