Actively Recruiting
Xeomin® and Gait Related Mobility After Stroke
Led by Wake Forest University Health Sciences · Updated on 2025-11-25
20
Participants Needed
1
Research Sites
284 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
M
Merz Pharmaceuticals GmbH
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).
CONDITIONS
Official Title
Xeomin® and Gait Related Mobility After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of hemiparesis and spasticity secondary to stroke with upper and lower limb spasticity and unilateral motor and/or sensory deficit
- No prior surgery to the lower limb
- Able to walk at least 10 meters without physical assistance from another person and without an assistive device
- Toe-ground clearance during swing phase without assistive device or orthoses
- No treatment with botulinum toxin within the past 4 months
You will not qualify if you...
- Passive range of motion at either the ankle, knee, or elbow joint less than 30 degrees
- Participants with uncorrected hearing impairment
- Weight bearing restrictions due to concurrent orthopedic injuries that would make ambulating with or without an assistive device unsafe
- Speech language expression deficit (e.g., aphasia)
- Absence of proprioception upon neurologic examination
- Presence of fixed contractures in the upper or lower extremities not correctable to neutral
- Other confounding neurological diagnoses or active acute illness (cancer, Parkinson's disease, multiple sclerosis)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Carolinas Rehabilitation
Charlotte, North Carolina, United States, 28203
Actively Recruiting
Research Team
M
Mark A Hirsch, PhD
CONTACT
K
Kiandra Austrie, RN, BSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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