Actively Recruiting
A 15-year Cohort Study on Risk Factors of Mortality in Patients With Intestinal Tuberculosis
Led by Beijing Chest Hospital, Capital Medical University · Updated on 2026-05-08
500
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study adopts a combined design of retrospective cohort study followed by prospective observational study, which is conducted at Beijing Chest Hospital. The study first collects and analyzes the data of intestinal tuberculosis patients diagnosed and followed up in the hospital from 2011-1 to 2025-12 (a 15-year retrospective period) as the retrospective cohort, aiming to initially identify the risk factors associated with mortality in patients with intestinal tuberculosis. On the basis of the retrospective analysis results, the study will further carry out a prospective observational study, continuously enroll new intestinal tuberculosis patients, follow up their clinical status, treatment response and mortality outcomes for a certain period, and verify and supplement the risk factors identified in the retrospective stage. Clinical data, including demographic characteristics, clinical manifestations, laboratory test results, treatment regimens, and follow-up outcomes (mortality status), will be collected and sorted out in both stages. Univariate and multivariate statistical analyses will be used to screen and verify potential risk factors (such as age, disease severity, comorbidities, and treatment compliance) that affect the mortality of patients with intestinal tuberculosis. The results of this study are expected to provide scientific evidence for optimizing the clinical management, risk assessment, and prognostic improvement of patients with intestinal tuberculosis, and further guide the formulation of targeted prevention and treatment strategies.
CONDITIONS
Official Title
A 15-year Cohort Study on Risk Factors of Mortality in Patients With Intestinal Tuberculosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older at the time of intestinal tuberculosis diagnosis
- Diagnosed with intestinal tuberculosis based on clinical, laboratory, imaging, and/or pathological evidence
- For the retrospective cohort: diagnosis between January 2011 and December 2025 with complete medical records and follow-up data including mortality status
- For the prospective cohort: newly diagnosed, able to cooperate with regular follow-up, and willing to sign informed consent if applicable
- No severe cognitive impairment or mental illness affecting data collection or follow-up
You will not qualify if you...
- Incomplete diagnosis of intestinal tuberculosis without clear clinical, laboratory, imaging, or pathological confirmation
- Concurrent severe extrapulmonary tuberculosis that may affect mortality outcomes
- For the retrospective cohort: incomplete medical records or missing key follow-up data, especially mortality status
- For the prospective cohort: refusal to sign informed consent, inability to cooperate with follow-up, or lost to follow-up
- Severe comorbidities likely to cause rapid death during the study period such as advanced cancer, severe heart failure, or end-stage liver/kidney disease
- Cognitive impairment, mental illness, or other conditions preventing effective clinical information provision or study cooperation
AI-Screening
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Trial Site Locations
Total: 1 location
1
Beijing Chest Hospital
Beijing, Beijing Municipality, China, 101149
Actively Recruiting
Research Team
X
Xuelian X Li, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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