Houston Emergency Response Opioid Engagement Program for Youths Aged 13 to 17 Combining Medication and Behavioral Support for Opioid Dependence

What this Trial Is About

Researchers are evaluating the Houston Emergency Response Opioid Engagement System for Youths and Adolescents Young HEROES, a community-based program designed to support youths with opioid use disorder OUD. The study aims to compare how different approaches affect engagement and retention in treatment, while understanding the rates of opioid overdoses and OUD among youth in Houston. This non-randomized cohort study involves youths aged 13 to 17 who have experienced opioid dependence or overdose. The study provides treatment involving same-day induction into medication for opioid use disorder MOUD using an 8mg buprenorphine2mg naloxone combination, combined with behavioral counseling, peer recovery support, and assertive outreach by a paramedic and peer coach. Participants receive ongoing maintenance treatment, referrals to youth-focused support groups, and long-term MOUD provider referrals. Weekly outreach efforts support youths after opioid overdoses to encourage treatment initiation. Participants will be assessed on engagement and retention in outpatient treatment 30 days after enrollment, along with opioid abstinence. Researchers also monitor quality of life, relapse rates, and frequency of opioid emergencies over an average of three years. Assessments include drug screening and medical evaluations, while peer support is available 247. Participation involves signing informed consent and assent, with monitoring of safety and treatment adherence throughout the study period ending in August 2030.

Young Houston Emergency Opioid Engagement System