Actively Recruiting
Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Led by Centre for Infectious Disease Research in Zambia · Updated on 2025-08-24
1200
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
Sponsors
C
Centre for Infectious Disease Research in Zambia
Lead Sponsor
U
University of Illinois at Chicago
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed hybrid effectiveness-implementation study will systematically adapt the Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (IMARA) curriculum that was previously adapted for South Africa (IMARA-SA) to use in Zambia (will be renamed Zambian Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (ZAIMARA) and evaluate the impact of ZAIMARA on improving adolescent girls and young women HIV testing, HIV and STI incidence, PrEP uptake and sexual risk behaviour. The study will also assess the impact of monthly mental health screening with referral versus a monthly nutrition and exercise screening on peer leaders job retention. We will also examine implementation factors and outcomes associated with ZAIMARA across five sites.
CONDITIONS
Official Title
Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female adolescent girls and young women aged 15 to 19 years (sex assigned at birth)
- Unmarried
- Reside outside the five study catchment areas
- Speak Nyanja, Bemba, English, or a combination of these languages
- Willing and able to provide consent if over 18 years or assent if under 18
- Not known to be living with HIV (no positive test and not on ART)
- Mother figures selected by AGYW, over 24 years old, living with or in daily contact with AGYW, speak Nyanja, Bemba, English, or combination, and willing to provide consent
- Peer leaders living in the community with prior experience working with young people
- Peer leaders have minimum grade 12 education and proficiency in reading and writing English and/or Nyanja or Bemba
- Peer leaders aged 22-29 years for AGYW sessions and over 30 years for MF sessions
You will not qualify if you...
- AGYW enrolled in other sexual and reproductive health interventions at recruitment
- AGYW known to be living with HIV
- AGYW who test positive for HIV at baseline will complete workshops but referred for treatment to avoid stigma
AI-Screening
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Trial Site Locations
Total: 1 location
1
Chainda, Matero, Chelston, Chongwe and Kalingalinga
Lusaka, Lusaka Province, Zambia, 10101
Actively Recruiting
Research Team
C
Carolyn Bolton
CONTACT
G
Geri Donenberg
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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