Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
NCT04984291

Zimmer Biomet Shoulder Arthroplasty PMCF

Led by Zimmer Biomet · Updated on 2026-04-28

584

Participants Needed

17

Research Sites

628 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.

CONDITIONS

Official Title

Zimmer Biomet Shoulder Arthroplasty PMCF

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient must be 20 years of age or older.
  • Patient must be anatomically and structurally suited to receive shoulder arthroplasty implants.
  • Patient is a candidate for shoulder arthroplasty due to one or more of the following: non-inflammatory degenerative joint disease including osteoarthritis and avascular necrosis, rheumatoid arthritis, correction of functional deformity, fractures of the proximal humerus where other treatments are inadequate, or difficult clinical management problems.
  • Patient must be able and willing to complete the protocol required follow-up.
  • Patient must be able and willing to sign the IRB/EC approved informed consent.
  • Patient has grossly deficient rotator cuff (for reverse application) with severe arthropathy and/or previously failed shoulder joint replacement.
  • Patient must have functional deltoid muscle (for reverse application).
Not Eligible

You will not qualify if you...

  • Patient is unwilling or unable to give consent or comply with the follow-up program.
  • Patient has any condition that would place them at undue risk or interfere with the study, as judged by the Investigator.
  • Patient is known to be pregnant or breastfeeding.
  • Patient is a vulnerable subject such as prisoner, mentally incompetent, alcohol or drug abuser, or anticipated to be non-compliant.
  • Patient is uncooperative or has neurologic disorders preventing following directions.
  • Patient has any infection near the shoulder joint that may spread to the implant site.
  • Patient has rapid joint destruction, marked bone loss, or bone resorption on X-rays.
  • Patient has neuromuscular disease compromising the affected limb.
  • Patient has osteoporosis that may limit support for the implant.
  • Patient has osteomalacia or metabolic bone disorders impairing bone formation.
  • Patient has deficient rotator cuff.
  • Patient has significant injury to upper brachial plexus.
  • Patient has paralysis of the axillary nerve.
  • Patient has non-functional deltoid or external rotator muscles.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 17 locations

1

Hoag Orthopedic Institute

Irvine, California, United States, 92618

Active, Not Recruiting

2

Panorama Orthopaedic and Spine Center

Golden, Colorado, United States, 80401

Actively Recruiting

3

Northwestern University

Chicago, Illinois, United States, 60208

Active, Not Recruiting

4

Norton Healthcare, Inc

Louisville, Kentucky, United States, 40202

Terminated

5

William Beaumont Hospital

Royal Oak, Michigan, United States, 48073

Active, Not Recruiting

6

TRIA Orthopaedic Center Research Institute

Bloomington, Minnesota, United States, 55431

Active, Not Recruiting

7

Mississippi Sports Medicine and Orthopaedic Center, PLLC

Jackson, Mississippi, United States, 39202

Active, Not Recruiting

8

Advance Bone and Joint

City of Saint Peters, Missouri, United States, 63376

Active, Not Recruiting

9

Washington University

St Louis, Missouri, United States, 63130

Active, Not Recruiting

10

University of Buffalo

Buffalo, New York, United States, 14215

Active, Not Recruiting

11

Rothman Institute

Philadelphia, Pennsylvania, United States, 19107

Active, Not Recruiting

12

Intermountain Health

Murray, Utah, United States, 84107

Actively Recruiting

13

Fukui General Hospital

Fukui, Japan, 910-3113

Active, Not Recruiting

14

Iwaki City Medical Center

Fukushima, Japan, 973-8555

Active, Not Recruiting

15

Yuuai Medical Center

Okinawa, Japan, 901-0224

Active, Not Recruiting

16

Kichijoji Minami Hospital

Tokyo, Japan, 180-0003

Withdrawn

17

Kensington Private Hospital

Whangarei, New Zealand, 0112

Withdrawn

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Research Team

C

Cayla Lafollette, BS

CONTACT

R

Ryan Boylan, MBA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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