Actively Recruiting
Zinc Oxide Versus Petrolatum Following Skin Surgery
Led by Melissa Pugliano-Mauro · Updated on 2025-08-14
30
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this split scar, head to head study comparing zinc oxide and petrolatum. Patients will apply respective ointments to each half of scar daily for one month and maintain a log of these activities. They will be seen at 1 week, 4 weeks, 8 weeks, and 6 months post-operatively for photographic scar assessment and to complete the patient portion of the Patient and Observer Scar Assessment Scale (POSAS), a quantitative objective assessment of scar appearance. Trained observers (board-certified dermatologists) will score the observer portion of the scale. POSAS outcomes, post-operative infections, linear density of epidermal seal will be assessed at the 1 week, 4 weeks, 8 weeks, and 6 months post-operative periods and compared between the two groups. Participants will have parking validated for all visits and upon completion of all portions of the study will receive a standardized skin care gift bag containing samples for hypoallergenic skin care products (washes, moisturizers, etc.).
CONDITIONS
Official Title
Zinc Oxide Versus Petrolatum Following Skin Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Linear closure on non-scalp skin
- Scar length of 4.5 cm or longer
- Surgical site shows end-to-end symmetry
- Surgical site is not infected
You will not qualify if you...
- Under 18 years of age
- Scar is visibly asymmetric
- Surgical site is visibly infected
- Known allergy to topical zinc oxide
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
UPMC Dermatology St. Margaret
Pittsburgh, PA, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
L
Lauren Crow, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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