Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT04263792

[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects

Led by University of Pennsylvania · Updated on 2026-02-05

20

Participants Needed

1

Research Sites

360 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose of this study is to study a radioactive tracer, a type of imaging drug that is injected into the body to see how it is taken up in sites of active infection using an imaging procedure called Positron Emission Tomography/Computed Tomography (PET/CT).

CONDITIONS

Official Title

[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years of age
  • Known or suspected bacterial infection confirmed by clinical documentation such as lab results, pathology, physician notes, or infection symptoms
  • Able to understand the study and provide written informed consent according to guidelines
Not Eligible

You will not qualify if you...

  • Receiving trimethoprim antibiotic therapy within 48 hours before the baseline PET/CT scan
  • Unable to tolerate imaging procedures as judged by the investigator or treating physician
  • Having unstable or severe medical or psychological conditions that compromise safety or study participation
  • Pregnant or breastfeeding; women of childbearing potential must have a negative urine pregnancy test before tracer injection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

E

Erin Schubert

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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