Completed

Phase 2
Age: 8Years - 13Years
FEMALE
Healthy Volunteers
ID00000402

Long Term Effects of Calcium on Bone Mass in Young Females

Led by Ohio State University · Updated on 2013-05-22

354

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

O

Ohio State University

Lead Sponsor

N

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls. At the start of this 7-year study, the average age of the girls was 11 years, and they had not yet reached puberty. The study will also provide information about the effect of calcium on body composition (body fat) and blood pressure in young women. We have been giving calcium to one group of participants in this study and giving a placebo (an inactive pill, or "sugar pill") to the other group. The results of this research will be important in preventing osteoporosis, because building more bone as a young person should reduce a woman's chances of developing osteoporosis later in life.

CONDITIONS

Official Title

Calcium and Bone Mass in Young Females

Who Can Participate

Age: 8Years - 13Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pubertal stage II
  • Calcium intake below a threshold level
  • Caucasian
  • Normal health
Not Eligible

You will not qualify if you...

  • Medications affecting calcium and bone metabolism
  • Chronic diseases
  • Metabolic bone disease
  • Abnormality in calcium metabolism

Trial Site Locations

Total: 1 location

1

OSU Bone and Mineral Metabolism Laboratory

Columbus, Ohio, United States, 43210

Status Unknown

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

0

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Published Research Related To This Trial

Timing of peak bone mass in Caucasian females and its implication for the prevention of osteoporosis. Inference from a cross-sectional model.

V Matkovic, T Jelic, G M Wardlaw...

https://pubmed.ncbi.nlm.nih.gov/8113412

Factors that influence peak bone mass formation: a study of calcium balance and the inheritance of bone mass in adolescent females.

V Matkovic, D Fontana, C Tominac...

https://pubmed.ncbi.nlm.nih.gov/2239765

Nutrition influences skeletal development from childhood to adulthood: a study of hip, spine, and forearm in adolescent females.

Velimir Matkovic, John D Landoll, Nancy E Badenhop-Stevens...

https://pubmed.ncbi.nlm.nih.gov/14988471