Unrelated donor hematopoietic cell transplantation: marrow or umbilical cord blood?
Satkiran S Grewal, Juliet N Barker, Stella M Davies...
https://pubmed.ncbi.nlm.nih.gov/12522002Completed
Phase 3
Age: 1Year - 55Years
All Genders
ID00000591
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2016-04-15
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To determine if a reduction in morbidity and mortality from acute and chronic graft versus host disease (GvHD) can be achieved through use of T-cell depletion techniques without a counterbalancing increase in relapse of leukemia in patients receiving an unrelated donor marrow transplant.
CONDITIONS
Official Title
T-Cell Depletion in Unrelated Donor Marrow Transplantation
Who Can Participate
Age: 1Year - 55Years
All Genders
Eligibility Criteria
You may qualify if you...
No eligibility criteria
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
Similar Trials
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Polyclonal engraftment after unrelated donor bone marrow and cord blood transplantation.
S M Davies, G A Radloff, J E Wagner...
https://pubmed.ncbi.nlm.nih.gov/9502297Unrelated donor bone marrow transplantation for children and adolescents with aplastic anaemia or myelodysplasia.
S M Davies, J E Wagner, T Defor...
https://pubmed.ncbi.nlm.nih.gov/9074418Unrelated donor bone marrow transplantation for hematological malignancies-current status.
S M Davies, J E Wagner, D J Weisdorf...
https://pubmed.ncbi.nlm.nih.gov/9031102Unrelated donor bone marrow transplantation for acute leukemia in patients with Down's syndrome.
A B Pawlowska, S M Davies, P J Orchard...
https://pubmed.ncbi.nlm.nih.gov/8864463Idiopathic hyperammonemia: a frequently lethal complication of bone marrow transplantation.
S M Davies, E Szabo, J E Wagner...
https://pubmed.ncbi.nlm.nih.gov/8807124Unrelated donor bone marrow transplantation for Fanconi anemia.
S M Davies, S Khan, J E Wagner...
https://pubmed.ncbi.nlm.nih.gov/8673053Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation.
Steven Z Pavletic, Shelly L Carter, Nancy A Kernan...
https://pubmed.ncbi.nlm.nih.gov/16046530Economic analysis of unrelated allogeneic bone marrow transplantation: results from the randomized clinical trial of T-cell depletion vs unmanipulated grafts for the prevention of graft-versus-host disease.
G de Lissovoy, D Hurd, S Carter...
https://pubmed.ncbi.nlm.nih.gov/16044144Issues in the quality of umbilical cord blood stem cells for transplantation.
Jeffrey McCullough, David McKenna, Diane Kadidlo...
https://pubmed.ncbi.nlm.nih.gov/15934980