Inclusion Criteria

Patients must have:

• Serologically confirmed HIV-1 infection.
• CD4 count >= 400/mm3.

Exclusion Criteria

Co-existing Condition:

Patients with any of the following conditions or symptoms are excluded:

• Symptoms of HIV-1 disease, except lymphadenopathy.
• Symptoms of cardiac disease.
• Evidence of clinical pulmonary disease.
• Significant medical disease.

Patients with any of the following prior conditions are excluded:

• History of symptoms of HIV-1 disease, except lymphadenopathy.
• Participation in another experimental AIDS treatment clinical trial within 4 weeks into entry.
• History of significant psychiatric disease.
• History of pancreatitis, history of neuropathy or neurotoxic drug therapy.
• History of serious allergies requiring either systemic steroid therapy or prior hospitalization.
• History of significant arrhythmia, infarction or heart failure. Immunomodulatory therapy such as steroids or cyclosporine, systemic chemotherapy or alpha-interferon.

Prior Medication: Exclusion:

• Past treatment with any protease inhibitor.
• History of neurotoxic drug therapy.

Risk Behavior: Excluded

• Patients with current substance abuse.
• Excessive alcohol intake.