Completed
The Effect of Oral and Injectable Contraceptives NorethindroneEthinyl Estradiol, Medroxyprogesterone Acetate and Gender on Plasma and Intracellular Zidovudine Pharmacokinetics
Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2011-03-02
42
Participants Needed
6
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
The purpose of this study is to look at the effects of different methods of birth control (oral and injectable) on how the body absorbs, makes available, and removes zidovudine (ZDV). This study will also evaluate the differences in men and women in how the body absorbs, makes available, and removes ZDV. Past research has shown that the effectiveness of ZDV as an anti-HIV drug might be decreased in individuals who use certain methods of birth control. ZDV may also have different effects in men compared to women.
CONDITIONS
Brief Title
A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and Women
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