Status:
COMPLETED
A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive Patients
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
HIV Infections
Eligibility:
All Genders
13+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to compare 4 different combinations of anti-HIV drugs and to determine the number of people whose HIV blood levels decrease to 200 copies/ml or less while on the treatment...
Detailed Description
A number of studies both within and outside the ACTG have been initiated or are in development to try to address the issue of alternative treatments for patients who either do not achieve or lose viro...
Eligibility Criteria
Inclusion Criteria
Patients may be eligible for this study if they:
- Are HIV-positive.
- Have current virologic failure (2 consecutive HIV blood levels above 1,000 copies/ml) while on PIs.
- Are over 13 years of age (consent of parent or guardian required if under 18).
- Agree to practice abstinence or use effective methods of birth control during the study and for 90 days after.
Exclusion Criteria
Patients will not be eligible for this study if they:
- Have hepatitis within 90 days prior to study entry.
- Have a history of a peripheral neuropathy within 60 days of study entry.
- Have an unexplained temperature for a 7-day period.
- Have chronic diarrhea within 30 days prior to study entry.
- Have cancer requiring chemotherapy.
- Received any therapy for infection or other illness within 30 days prior to study entry.
- Have received certain other medications.
- Are pregnant or breast-feeding.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
May 1 2000
Estimated Enrollment :
475 Patients enrolled
Trial Details
Trial ID
NCT00000912
End Date
May 1 2000
Last Update
October 29 2021
Active Locations (45)
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1
Univ of Southern California / LA County USC Med Ctr
Los Angeles, California, United States, 900331079
2
USC Univ Hosp & Ambulatory Hlth Care Ctr / USC Med Ctr
Los Angeles, California, United States, 900334508
3
UCLA CARE Ctr
Los Angeles, California, United States, 90095
4
Willow Clinic
Menlo Park, California, United States, 94025