Inclusion Criteria

You may be eligible for this study if you:

• Are HIV-positive.
• Have a CD4+ cell count less than 150 cells/mm3.
• Had at least one episode of thrush in the 24 months before study entry.
• Have a life expectancy of at least 12 months.
• Weigh at least 88 pounds.
• Are 13 years of age or older (consent of parent or guardian required if under 18).
• Agree to practice abstinence or use effective methods of birth control during the study.

Exclusion Criteria

You will not be eligible for this study if you:

• Have an allergy to azoles.
• Have had 3 episodes or more of thrush within 12 weeks of study entry.
• Have a history of esophageal candidiasis.
• Have a history of fluconazole-resistant infection.
• Have an active opportunistic infection requiring treatment within 14 days before study entry.
• Have a fungal infection requiring certain medications.
• Have a severe liver disease (e.g., cirrhosis).
• Are unable to tolerate oral medications.
• Take certain medications.
• Are pregnant or breast-feeding.