Complex partial seizures: clinical characteristics and differential diagnosis.
W H Theodore, R J Porter, J K Penry
https://pubmed.ncbi.nlm.nih.gov/6684245Completed
All Genders
ID00001149
Monitoring of Seizures, EEG and Serum Antiepileptic Drug Concentrations in Patients With Uncontrolled Epilepsy
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2008-03-04
900
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is designed to evaluate patients with uncontrolled seizures. Seizures can be associated with and monitored by abnormal electrical activity in the brain. In this study researchers will use video-electroencephalography (EEG) to monitor patients with uncontrolled or suspected seizures. EEG works by measuring electrical activity in different areas of the brain. The video-EEG allows researchers to examine changes in the EEG along with the clinical features of seizures as they occur. In addition to monitoring electrical activity of the brain, researchers will take frequent antiepileptic drug blood levels. These measures will allow researchers to learn more about how each drug is absorbed and metabolized in the body. The information collected in the study will be used to place patients into other scientific studies testing new therapies for epilepsy.
CONDITIONS
Official Title
Monitoring Patients With Uncontrolled Epilepsy
Who Can Participate
All Genders
Eligibility Criteria
You may qualify if you...
History of uncontrolled seizures, at the present time, at least during 6 months of the past 3 years, and preferably a continuous pattern of seizures during the few months prior to admission.
Seizure frequency, by history, must be sufficient to make video monitoring effective. Priority will be given to patients whose seizures occur once or more per day.
Patients of any age may be accepted.
Patients (and parents or guardians, if applicable) must express willingness to cooperate with the entire protocol, to be willing to undergo further diagnostic tests if needed, and to return for follow up evaluation at intervals as needed.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Simultaneous recording of absence seizures with video tape and electroencephalography. A study of 374 seizures in 48 patients.
J K Penry, R J Porter, R E Dreifuss
https://pubmed.ncbi.nlm.nih.gov/1182486Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
L L Altshuler, O Devinsky, R M Post...
https://pubmed.ncbi.nlm.nih.gov/2106868