A randomized clinical trial of CPI-1189 for HIV-associated cognitive-motor impairment.
D B Clifford, J C McArthur, G Schifitto...
https://pubmed.ncbi.nlm.nih.gov/12451199Status Unknown
Phase 2
Age: 18Years +
All Genders
ID00002414
Randomized, Double-Blind, Parallel Group, Placebo Controlled, Tolerability, Safety and Pilot Efficacy Study of CPI-1189 in HIV Infected Individuals With Cognitive and Motor Impairment
Led by Centaur Pharmaceuticals · Updated on 2005-06-24
60
Participants Needed
6
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to see if it is safe and effective to give CPI-1189 to patients with AIDS dementia. Advanced HIV infection can cause AIDS dementia (brain damage due to HIV leading to loss of memory and muscle control). CPI-1189 may be able to postpone AIDS dementia or slow it down.
CONDITIONS
Official Title
Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive.
- Are at least 18 years old.
- Have symptoms of AIDS dementia including forgetfulness, loss of concentration, slow mental processing, or a loss of muscle control.
- Have been on stable anti-HIV drug therapy for the past 6 weeks (if you are taking anti-HIV drugs).
Exclusion Criteria
You will not be eligible for this study if you:
- Have certain serious medical conditions, such as a mental disorder or an opportunistic (AIDS-related) infection.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 6 locations
1
Alzheimers Disease Research Ctr 0948 / UCSD
San Diego, California, United States, 920930948
Status Unknown
2
Northwestern Univ / Dept of Neurology
Chicago, Illinois, United States, 60611
Status Unknown
3
Johns Hopkins Hosp / Dept of Neurology / Meyer 6109
Baltimore, Maryland, United States, 212877609
Status Unknown
4
Washington Univ Sch of Med / Dept of Neurology
St Louis, Missouri, United States, 63110
Status Unknown
5
Columbia Univ / Sergievsky Ctr Physicians and Surgeons
New York, New York, United States, 10032
Status Unknown
6
Univ of Rochester / Strong Memorial Hosp
Rochester, New York, United States, 14620
Status Unknown
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
N/A
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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