Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06071377

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Led by National Alliance for Sickle Cell Centers · Updated on 2025-11-06

1000

Participants Needed

10

Research Sites

200 weeks

Total Duration

On this page

Sponsors

N

National Alliance for Sickle Cell Centers

Lead Sponsor

B

Beam Therapeutics Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.

CONDITIONS

Official Title

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to voluntarily participate and sign the study consent
  • Know or suspect they have SCT and agree to get tested to confirm or learn their SCT status
  • Adults aged 18 years and older
Not Eligible

You will not qualify if you...

  • Unwilling to sign consent
  • Known end-stage renal disease or on dialysis
  • Diagnosed with sickle cell disease, including sickle cell-beta thalassemia
  • Do not have sickle cell trait

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 10 locations

1

University of Alabama

Birmingham, Alabama, United States, 35294

Actively Recruiting

2

Loma Linda University Health Care

Loma Linda, California, United States, 92354

Actively Recruiting

3

Nemours Children's Hospital

Wilmington, Delaware, United States, 19803

Actively Recruiting

4

Indiana University

Indianapolis, Indiana, United States, 46202

Actively Recruiting

5

Functional Fluidics

Detroit, Michigan, United States, 48202

Actively Recruiting

6

University of North Carolina

Chapel Hill, North Carolina, United States, 27599

Actively Recruiting

7

Duke University

Durham, North Carolina, United States, 27710

Actively Recruiting

8

East Carolina University

Greenville, North Carolina, United States, 27834

Actively Recruiting

9

Nationwide Children's Hospital

Columbus, Ohio, United States, 43205

Actively Recruiting

10

UT Health Houston

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

J

Julie Kanter, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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