Actively Recruiting
Acute Hepatitis in Pediatrics
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-07
437
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how acute hepatitis presents in children, focusing on the symptoms and blood test changes associated with this condition. The study aims to better understand the frequency of different symptoms, blood test abnormalities, and any complications that may arise from pediatric acute hepatitis. This observational study collects and analyzes patient data without altering standard medical care. The study observes children aged 0 to 17 years diagnosed with acute hepatitis who access Pediatric Emergency Rooms or are hospitalized. Researchers will document clinical signs, symptoms, and laboratory findings such as liver enzyme levels (AST, ALT, ALP, GGT) and coagulation markers to characterize the disease presentation and its variations by age and etiology. The study does not involve any experimental treatments or interventions. Participants will have their clinical course followed through routine medical care. Data collection includes symptoms, blood tests, and monitoring for severe outcomes like acute liver failure. The primary outcome is to describe how clinical and laboratory features vary with age and underlying causes of acute hepatitis. The study duration averages one year per participant and is conducted without interfering with normal treatment or hospital procedures.
CONDITIONS
Brief Title
Acute Hepatitis in Pediatrics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 0 and 17 years (extremes included)
- Access to Pediatric Emergency Room and/or hospitalization
- Diagnosis of acute hepatitis
You will not qualify if you...
- Parent or guardian refuses to participate in the study
- Mild elevation of liver enzymes (less than 5 times upper normal limit) in patient with known chronic liver disease
- Neonatal jaundice without liver cell involvement or signs of cholestasis
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Through study completion, an average of 1 year
Participants who have been diagnosed with acute hepatitis are observed to study the clinical and laboratory presentation and how it varies according to age group and different etiologies.
Participants have visits as needed during their care in Pediatric Emergency Room or hospitalization
Trial Site Locations
Total: 2 locations
1
Azienda USL di Bologna Ospedale Maggiore
Bologna, Italy, 40124
Actively Recruiting
2
IRCCS Azienda Ospedaliero - Universitaria di Bologna
Bologna, Italy, 40138
Actively Recruiting
Research Team
A
Arianna Dondi
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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