Observational Study on Acute Hepatitis in Children and Adolescents up to 17 Years Understanding Symptoms, Blood Test Changes, and Disease Progression

What this Trial Is About

Researchers are investigating how acute hepatitis presents in children, focusing on the symptoms and blood test changes associated with this condition. The study aims to better understand the frequency of different symptoms, blood test abnormalities, and any complications that may arise from pediatric acute hepatitis. This observational study collects and analyzes patient data without altering standard medical care. The study observes children aged 0 to 17 years diagnosed with acute hepatitis who access Pediatric Emergency Rooms or are hospitalized. Researchers will document clinical signs, symptoms, and laboratory findings such as liver enzyme levels AST, ALT, ALP, GGT and coagulation markers to characterize the disease presentation and its variations by age and etiology. The study does not involve any experimental treatments or interventions. Participants will have their clinical course followed through routine medical care. Data collection includes symptoms, blood tests, and monitoring for severe outcomes like acute liver failure. The primary outcome is to describe how clinical and laboratory features vary with age and underlying causes of acute hepatitis. The study duration averages one year per participant and is conducted without interfering with normal treatment or hospital procedures.

Acute Hepatitis in Pediatrics