Actively Recruiting
Additive Efficacy of Physical Activity Program in Hypothyroidism Elder Females With Glaucoma and Fatty Liver Issues
Led by Cairo University · Updated on 2026-05-20
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the added benefits of a physical activity program for older women who have subclinical hypothyroidism, glaucoma, and non-alcoholic fatty liver disease. This study aims to understand how exercise combined with usual thyroid hormone treatment may affect these conditions, particularly focusing on eye pressure and other health measures. The research involves elder females aged 65 to 75 years and is sponsored by Cairo University. Participants will be randomly assigned to one of two groups: one group will receive their regular levothyroxine treatment along with a treadmill exercise program three times a week for six months. The second group will receive only the levothyroxine treatment without the exercise program. This comparison will help determine the effects of adding physical activity to the usual care. During the six-month study, participants will have various health assessments, including eye pressure measurement, body weight, waist size, blood pressure, blood tests for liver enzymes and lipids, thyroid hormone levels, and quality of life surveys related to glaucoma and physical and mental health. These evaluations will help researchers monitor changes and safety throughout the study period.
CONDITIONS
Brief Title
Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subclinical hypothyroidism (significant form)
- Primary open angle glaucoma in both eyes with ocular hypertension (high-tension type glaucoma)
- Non-alcoholic fatty liver disease
- Elder females aged 65 to 75 years
You will not qualify if you...
- Respiratory issues
- Cardiac issues
- Renal issues
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Participants receive levothyroxine, with some also participating in a physical activity program on a treadmill three times weekly.
Weekly visits for up to 6 months
Trial Site Locations
Total: 1 location
1
Cairo University
Dokki, Giza Governorate, Egypt, 11432
Actively Recruiting
Research Team
A
Ali MA Ismail, lecturer
F
fatma M Ali
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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