Actively Recruiting

Age: 3Years - 3Years
All Genders
Healthy Volunteers
NCT06957509

Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment

Led by Karolinska Institutet · Updated on 2025-05-04

100

Participants Needed

1

Research Sites

138 weeks

Total Duration

On this page

Sponsors

K

Karolinska Institutet

Lead Sponsor

F

Folktandvården Stockholms län AB

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for caries risk. The main question to answer is: • Can the host´s salivary protein profile (expression and abundance) show a correlation with the caries prevalence between the individuals in the different study cohorts? Two cohorts of children with different documented demographic characteristics in the region of Stockholm (Sweden) will be examined. Participants will be asked to provide saliva samples and undergo clinical oral examinations conducted by trained dental practitioners.

CONDITIONS

Official Title

Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment

Who Can Participate

Age: 3Years - 3Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Child is 3 years old and lives in areas served by Folktandv�e5rden Danderyd or J�e4rva
  • Written consent signed by both parents or guardians
Not Eligible

You will not qualify if you...

  • Child is older than 3 years
  • Taking medication or antibiotics at the time of examination
  • Consumed food, drink, or used oral hygiene products within 2 hours before the dental visit
  • Child is uncooperative during saliva sampling

AI-Screening

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Trial Site Locations

Total: 1 location

1

Folktandvården Stockholms län AB

Stockholm, Sweden

Actively Recruiting

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Research Team

F

Franziska Anna Hetrodt, Dr. med. dent.

CONTACT

M

Maria Anderson, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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