Using Radiomics to Link Ultrasound Features with Breast Cancer Prognosis

What this Trial Is About

Researchers are exploring the relationship between ultrasound features, including conventional ultrasound, elastography, and contrast-enhanced ultrasound CEUS, and pathological prognostic factors in breast cancer. This observational study uses radiomics, a method that extracts detailed imaging information, to better understand these correlations and their potential clinical relevance. The study is sponsored by the Second Affiliated Hospital, School of Medicine, Zhejiang University, and aims to provide insights into breast cancer prognosis. Participants undergo ultrasound imaging assessments, including advanced techniques like elastography and CEUS, alongside standard pathological evaluations. The study observes patients over an average follow-up period of one year to monitor outcomes such as metastasis and death related to breast cancer progression. While endocrine therapy is noted as an intervention, the study primarily focuses on imaging and pathological data rather than treatment comparison. During the study, participants ultrasound characteristics and pathological findings are recorded and analyzed using radiomics technology. Researchers track disease-free survival and non-disease-free survival times, noting the time to relapse, metastasis, or death due to disease progression. Data collection includes follow-up results and pathology reports to ensure comprehensive monitoring. The total participation duration aligns with the one-year average follow-up to assess primary outcomes accurately.

Application of Radiomics in Breast Cancer