Actively Recruiting

Phase Not Applicable
Age: 45Years - 60Years
All Genders
ID07452276

Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke

Led by Omima Alaa Eldin Hussein · Updated on 2026-03-05

40

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating whether training based on an artificial intelligence (AI) application can improve cognitive function in patients who have experienced a stroke. The focus is on stroke patients with cognitive impairments, particularly those in the chronic stage of recovery at least three months after stroke onset. The study aims to assess the impact of AI-based training on multiple cognitive areas including attention, memory, executive function, and processing speed. Participants are randomly assigned to one of two groups. One group receives the AI-based cognitive training using the cognifit mobile application, which offers personalized exercises that adapt to individual performance. The other group undergoes a conventional rehabilitation program that includes aerobic exercise, relaxation activities, and traditional paper-based cognitive exercises, alongside standard physical therapy. Both programs are designed to match in duration and frequency. During the study, cognitive function is measured at the start and again six weeks after the interventions to track changes. Participants will be monitored for their ability to follow instructions and maintain medical stability. The primary outcome focuses on improvements in cognitive function as assessed by standardized tests. The entire study period spans at least six weeks of intervention with assessments to evaluate the effect of the training programs.

CONDITIONS

Brief Title

Artificial Intelligence-Based Cognitive Training in Patients With Stroke

Who Can Participate

Age: 45Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 45 and 60 years
  • Diagnosis of stroke in the chronic stage (3 months or more since onset)
  • Cognitive impairment with a Montreal Cognitive Assessment (MoCA) score of 26 or less
  • Medically stable and able to follow instructions
  • Presence of memory deficits following stroke
Not Eligible

You will not qualify if you...

  • Severe visual, hearing, or speech impairments that prevent participation
  • History of other neurological or psychiatric disorders
  • Unstable cardiovascular or systemic disease
  • Severe depression with Beck Depression Inventory score greater than 29

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 weeks

Participants engage in either artificial intelligence-based cognitive training or conventional cognitive rehabilitation targeting cognitive function after stroke.

Weekly visits for cognitive training and assessments

Follow-up

Duration - 6 weeks post-intervention

Participants are assessed for changes in cognitive function following the completion of the cognitive training program.

1 follow-up visit (in-person)

Trial Site Locations

Total: 1 location

1

Physical therapy- Cairo University

Cairo, Egypt, Egypt, 62517

Actively Recruiting

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Research Team

O

Omima Alaa Eldin Hussein

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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