Actively Recruiting

Phase Not Applicable
Age: 6Months - 24Months
All Genders
NCT06876259

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

Led by Timothy Shope · Updated on 2026-01-07

300

Participants Needed

2

Research Sites

82 weeks

Total Duration

On this page

Sponsors

T

Timothy Shope

Lead Sponsor

M

Merck Sharp & Dohme LLC

Collaborating Sponsor

AI-Summary

What this Trial Is About

Ear infections are common in young children with cold symptoms, but they can be difficult to diagnose due to small ear canals, child movement, and limited viewing time. In this study, investigators will take photos of the eardrums of children 6-24 months of age with upper respiratory symptoms. The photos will be reviewed by imaging software enhanced with artificial intelligence (AI app) to determine whether the AI app changes how ear infections are diagnosed and treated. The AI app has undergone rigorous study and was found to be highly accurate; but how using this technology affects the diagnosis and treatment by clinicians has not been studied. This research may help improve diagnostic accuracy for ear infections and ensure antibiotics are prescribed only for those children who have definite ear infections.

CONDITIONS

Official Title

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

Who Can Participate

Age: 6Months - 24Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 6-24 months
  • Presence of upper respiratory infection
Not Eligible

You will not qualify if you...

  • No upper respiratory infection
  • Otorrhea (ear drainage)
  • Tympanostomy tubes
  • Currently taking antimicrobials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Children's Community Pediatrics Brentwood

Pittsburgh, Pennsylvania, United States, 15227

Actively Recruiting

2

Children's Community Pediatrics Castle Shannon

Pittsburgh, Pennsylvania, United States, 15234

Actively Recruiting

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Research Team

T

Timothy R Shope, MD, MPH

CONTACT

N

Nader Shaikh, MD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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