Effect of a Multisectoral Agricultural Intervention on HIV Health Outcomes Among Adults in Kenya: A Cluster Randomized Clinical Trial.
Craig R Cohen, Elly Weke, Edward A Frongillo...
https://pubmed.ncbi.nlm.nih.gov/36508217Actively Recruiting
Phase Not Applicable
Age: 15Years +
All Genders
Healthy Volunteers
ID06953310
Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young Women
Led by University of California, San Francisco · Updated on 2026-04-13
900
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
K
Kenya Medical Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a multisectoral agricultural intervention called Shamba Maisha aimed at improving reproductive and sexual health among adolescent girls and young women (AGYW) aged 15-19 in Kisumu and Migori counties of Western Kenya. This region has high rates of HIV and sexually transmitted infections (STIs), along with widespread food insecurity and poverty, which contribute to vulnerability to these infections. The study focuses on reducing the incidence of gonorrhea and chlamydia and improving related health outcomes by addressing household food security and adolescent-caregiver relationships. The Shamba Maisha intervention includes providing families with water pumps, seeds, and farming tools, along with training on agricultural techniques delivered at both home and school demonstration farms. Girls will engage in practical farming activities at school, which also benefits the wider school community. Additionally, families participate in sessions to strengthen communication and reduce stress between caregivers and adolescents, including discussions on sexual health. Control group participants will have the chance to receive the full intervention after the study concludes. Participants will be followed for 18 months, with data collected through surveys and testing for STIs and pregnancy at four time points: baseline, 6, 12, and 18 months. Researchers will measure outcomes such as STI incidence, household food insecurity, adolescent and caregiver mental health, body mass index, condom use, intimate partner violence, empowerment, and educational attainment. The study will also assess factors affecting implementation and costs, aiming to inform sustainable strategies to reduce food insecurity and improve HIV prevention among vulnerable youth.
CONDITIONS
Brief Title
Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young Women
Who Can Participate
Age: 15Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Adolescent girls and young women assigned female at birth
- Aged 15 to 19 years at enrollment
- Attending selected schools with at least 18 months remaining of schooling
- STI-uninfected and not pregnant at baseline
- Has an adult caregiver willing to participate
- Demonstrates moderate to severe food insecurity and/or malnutrition (BMI below two standard deviations for age)
- Caregiver at least 18 years old
- Caregiver has at least one AGYW aged 15-19 attending the selected schools
- Household has access to farming land
- Household is within 200 meters of a permanent surface water source such as lakes, rivers, ponds, or shallow wells
You will not qualify if you...
- AGYW or caregivers with inadequate cognitive or hearing ability to complete study procedures
- AGYW or caregivers who do not speak Dholuo, Kiswahili, or English
- Married AGYW or those who are heads of households
- AGYW who are pregnant at screening
- AGYW testing positive for gonorrhea or chlamydia at screening without confirmatory negative test after treatment
AI-Screening
AI-Powered Screening
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Intervention
Duration - Up to 18 months
Participants receive the Shamba Maisha Intervention which includes farming equipment and training, school-based practical farming activities, and family sessions to improve communication and discuss sexual health.
Visits at baseline, 6, 12, and 18 months for assessments
Follow-up
Duration - Up to 18 months
Participants are assessed periodically to monitor health outcomes such as STI incidence, food security, mental health, and other measures.
Visits at baseline, 6, 12, and 18 months for assessments
Trial Site Locations
Total: 1 location
1
Kenya Medical Research Institute (KEMRI)
Kisumu, Kenya
Actively Recruiting
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Research Team
R
Rachel L Burger, MHS
J
Jennifer Velloza, PhD, MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Published Research Related To This Trial
Effect of improving food security on parenting practices and caregiver-adolescent relationships: qualitative findings of an income-generating agricultural intervention in rural Kenya.
Maricianah A Onono, Lila Sheira, Edward A Frongilio...
https://pubmed.ncbi.nlm.nih.gov/39721953Links between Household-Level Income-Generating Agricultural Intervention and the Psychological Well-Being of Adolescent Girls in Human Immunodeficiency Virus-Affected Households in Southwestern Kenya: A Qualitative Inquiry.
Maricianah A Onono, Edward A Frongillo, Lila A Sheira...
https://pubmed.ncbi.nlm.nih.gov/37863268The role of food security in increasing adolescent girls' agency towards sexual risk taking: qualitative findings from an income generating agricultural intervention in southwestern Kenya.
Maricianah A Onono, Gladys Odhiambo, Lila Sheira...
https://pubmed.ncbi.nlm.nih.gov/34742285