Innovative Approaches in Managing Chronic Low Back Pain: A Comparative Assessment of Clinical Techniques

What this Trial Is About

Researchers are evaluating different clinical techniques to treat patients with chronic low back pain (CLBP), a condition causing persistent pain for more than three months and affecting quality of life. The study compares conventional therapy using nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy with a combination of neuromodulation and platelet-rich plasma (PRP) therapy. The goal is to see if neuromodulation via the dorsal root ganglion and PRP can provide better pain relief and improve function by reducing inflammation and modulating nerve pathways. Participants will be assigned randomly to one of two groups. The conventional therapy group will take NSAIDs daily as prescribed and attend physical therapy sessions twice a week. The neuromodulation plus PRP group will receive weekly neuromodulation sessions via dorsal root ganglion for the first month, followed by monthly maintenance if needed, and weekly PRP injections for the first three weeks. Both treatments involve monitoring and adjustments during the study. Throughout the study, participants will be regularly assessed for pain levels using the Visual Analog Scale (VAS), disability using the Oswestry Disability Index (ODI), and anxiety and depression with the Hospital Anxiety Depression scale (HAD) at multiple time points up to 12 months. Researchers will monitor adherence, side effects, and functional improvements during scheduled visits. The study will last over a year to evaluate both short-term and long-term outcomes for chronic low back pain management.

Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain