Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06771960

Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC

Led by Guangdong Provincial People's Hospital · Updated on 2025-02-21

120

Participants Needed

1

Research Sites

47 weeks

Total Duration

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AI-Summary

What this Trial Is About

EGFR-mutated NSCLC is a distinct subtype that responds well to targeted therapies. Neoadjuvant targeted therapy aims to downstage tumors and improve surgical outcomes, but the prognostic role of residual viable tumor (RVT) remains unclear. This retrospective study examines the association between RVT and survival outcomes. The findings will further validate the importance of RVT as a surrogate.

CONDITIONS

Official Title

Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-80 years old
  • Pathologically diagnosed EGFR-mutated non-small cell lung cancer (NSCLC)
  • Treated with neoadjuvant targeted therapy
  • Undergoing definitive surgery
Not Eligible

You will not qualify if you...

  • History of prior chemotherapy, immunotherapy, or radiotherapy
  • History of malignancy or lung surgery
  • Missing key data

AI-Screening

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Trial Site Locations

Total: 1 location

1

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China, 510080

Actively Recruiting

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Research Team

G

Guibin Qiao

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC | DecenTrialz