Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07298356

Automated Applanation Tonometry - Updated

Led by Duke University · Updated on 2026-03-06

200

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating new methods to measure eye pressure more objectively, reproducibly, and portably compared to the current clinical standards. The study focuses on comparing two investigational devices with Goldmann Applanation Tonometry (GAT) and pneumotonometer, which are standard methods used to check eye pressure. This research is important for patients undergoing eye exams, especially those suspected of glaucoma or with glaucoma, to improve measurement accuracy and convenience. Participants will undergo four types of intraocular pressure (IOP) measurements in random order: standard GAT, fixed force GAT, an upright applanating prototype, and pneumotonometer. Standard GAT and pneumotonometer are established clinical methods involving topical anesthetic and direct eye contact. The fixed force GAT and upright applanating prototype are investigational devices that use cameras to record mire images and calculate IOP based on these images. The upright prototype is portable and uses blue LED lights to simulate standard clinical illumination. During the study, participants will have their IOP measured by each method during their scheduled eye appointment after giving consent. Researchers will track and compare the pressure readings from each device. The primary outcomes include IOP values measured by all four methods at baseline. This prospective study will help assess the repeatability and portability of the new devices compared to standard clinical tools, with no masking or blinding involved.

CONDITIONS

Brief Title

Automated Applanation Tonometry - Updated

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presenting for a routine eye exam
  • 18 years of age or older
  • Able and willing to give consent
Not Eligible

You will not qualify if you...

  • History of corneal scarring
  • Active infection of the eye
  • Ocular surface trauma or infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Single day

Participants undergo randomized intraocular pressure (IOP) measurements using four different devices including Standard Goldmann Applanation Tonometry, Fixed force GAT, Upright applanating prototype, and Pneumotonometer during a scheduled eye appointment.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Duke Eye Center

Durham, North Carolina, United States, 27710

Actively Recruiting

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Research Team

S

Sarah Jones

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

4

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