Actively Recruiting

Phase 2
Age: 18Years +
All Genders
ID05653440

Integrating Complementary Learning Principles in Aphasia Rehabilitation Via Adaptive Modeling (Sub-study 1: Balancing Effortful and Errorless Learning Using Adaptive Naming Deadlines)

Led by University of Pittsburgh · Updated on 2026-04-13

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

U

University of Massachusetts, Amherst

Collaborating Sponsor

AI-Summary

What this Trial Is About

Aphasia is a language disorder caused by stroke and other brain injuries that affects many people and impacts their ability to communicate and participate in daily life. This research focuses on anomia, a common difficulty in finding words, and aims to evaluate new treatment approaches that improve long-term retention of naming skills and their use in everyday situations. The study is part of a larger project and specifically investigates balancing effort and accuracy with adaptive speeded naming deadlines. Participants will receive three different naming treatment conditions in a randomized order: an accuracy-maximized condition where the target word is immediately provided, an effort-maximized condition allowing up to 10 seconds to respond before the target is given, and an effort-accuracy balanced condition where deadlines adapt based on individual performance. Each condition consists of eight treatment sessions over four weeks, with treatment time controlled to eight hours per condition. Treatments involve naming pictures with cues and feedback on accuracy. Participants will be assessed at baseline and followed up one week, three months, and six months after treatment using naming tests, language assessments, and questionnaires on communication effectiveness and motivation. Assessments include confrontation naming of treated and untreated objects, discourse analysis, and communication outcome measures. The study will last about 10 to 18 months per participant, with data collection occurring at the university lab, participants' homes, or private public spaces.

CONDITIONS

Brief Title

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of chronic aphasia lasting more than 6 months after left hemisphere ischemic or hemorrhagic stroke
  • Impaired performance on at least 2 out of 8 sections of the Comprehensive Aphasia Test
  • Adults aged 18 years or older
  • Male or female community-dwelling individuals
Not Eligible

You will not qualify if you...

  • History of other acquired or progressive neurological diseases
  • Significant impairments in language comprehension
  • Unmanaged drug or alcohol dependence
  • Severe diagnosed mood or behavioral disorders requiring specialized mental health treatment

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Treatment

Duration - Approximately 12 weeks (3 conditions, 4 weeks each)

Participants receive three different naming treatment conditions in a randomized order, each consisting of 8 sessions over 4 weeks with 2 sessions per week, focusing on adaptive naming deadlines to improve aphasia.

24 treatment sessions (2 sessions per week for 4 weeks per condition)

Follow-up

Duration - Up to 6 months post-treatment per condition

Participants complete follow-up assessments including probes at 1 week, 3 months, and 6 months after each treatment condition to measure treatment effects and communication changes.

Approximately 3 follow-up assessment sessions per condition

Trial Site Locations

Total: 1 location

1

Language Rehab and Cognition Lab, Department of Communication Sciences and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15260

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Research Team

A

Alyssa Kelly, M.A., CCC-SLP

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

6

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Published Research Related To This Trial

Adaptive balancing of effort, accuracy and response speed in anomia treatment for post-stroke aphasia in community-based settings in the USA: a within-subjects randomised controlled trial protocol.

Candace M van der Stelt, Robert Cavanaugh, William D Hula...

https://pubmed.ncbi.nlm.nih.gov/42161555