Study Comparing Full and Empty Bladder Approaches for Pelvic Radiation Therapy in Genitourinary, Gynecological, and Gastrointestinal Cancers

What this Trial Is About

This research aims to evaluate the effects of empty versus full bladder protocols during radiation therapy for common pelvic cancers affecting the genitourinary, gynecological, and gastrointestinal systems. Radiation therapy is important in treating these malignancies, but the typical full bladder approach can cause variations in bladder size, potentially altering radiation dose distribution and side effects. This study addresses the lack of prospective data comparing these two bladder preparation methods. Participants are randomly assigned to either a full bladder or empty bladder protocol for their CT simulation and subsequent radiation treatments. The full bladder protocol involves patients maintaining a full bladder as traditionally recommended, while the empty bladder protocol involves patients having an empty bladder during treatment. Both protocols are evaluated to understand their impact on radiation delivery and treatment outcomes. During the study, participants will undergo CT simulations and receive radiation therapy according to their assigned bladder protocol. Researchers will assess acute toxicity within three months after radiation treatment, focusing on side effects related to radiation exposure. Participants will be monitored throughout the treatment period to track any changes or complications. The study duration and follow-up extend at least three months post-radiation to evaluate these outcomes effectively.

BladdEr Full OR Empty for Pelvic Radiation Therapy