Mapping Brain Cognitive Network Changes in Adults Aged 18 to 65 with Anemia Using Functional Near-Infrared Spectroscopy

What this Trial Is About

Anemia is a widespread health issue linked to problems in brain cognitive neural networks, which are important for memory, learning, processing speed, and executive function. These cognitive impairments can reduce daily functioning and increase risks of falls and depression. Researchers are studying how anemia affects these brain networks to help detect cognitive problems early and improve treatment strategies. This research uses functional near-infrared spectroscopy fNIRS to monitor changes in oxygenated and deoxygenated hemoglobin in the brain, reflecting neural activity. The study aims to identify brain regions affected by anemia and visualize changes in connectivity through heatmaps and arc-based mapping. These insights will support personalized approaches to manage cognitive impairment in anemia patients. Participants diagnosed with anemia and hospitalized for the first time will be assessed within 48 hours of admission. Evaluations include measurements of hemoglobin concentrations using fNIRS and cognitive function tests. Additional assessments will examine anxiety, depression, sleep quality, physical fatigue, and appetite. The study will help understand brain function changes related to anemia and guide clinical care to improve quality of life.

Brain Cognitive Network Abnormalities in Anemia Patients Using fNIRS