Actively Recruiting
Construction of Abnormal Projection Regions of Cognitive Neural Networks in Patients With Anemia Using Functional Near-Infrared Spectroscopy (fNIRS)
Led by Institute of Hematology & Blood Diseases Hospital, China · Updated on 2026-05-11
323
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
Sponsors
I
Institute of Hematology & Blood Diseases Hospital, China
Lead Sponsor
T
Tianjin University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Anemia is a widespread health issue linked to problems in brain cognitive neural networks, which are important for memory, learning, processing speed, and executive function. These cognitive impairments can reduce daily functioning and increase risks of falls and depression. Researchers are studying how anemia affects these brain networks to help detect cognitive problems early and improve treatment strategies. This research uses functional near-infrared spectroscopy (fNIRS) to monitor changes in oxygenated and deoxygenated hemoglobin in the brain, reflecting neural activity. The study aims to identify brain regions affected by anemia and visualize changes in connectivity through heatmaps and arc-based mapping. These insights will support personalized approaches to manage cognitive impairment in anemia patients. Participants diagnosed with anemia and hospitalized for the first time will be assessed within 48 hours of admission. Evaluations include measurements of hemoglobin concentrations using fNIRS and cognitive function tests. Additional assessments will examine anxiety, depression, sleep quality, physical fatigue, and appetite. The study will help understand brain function changes related to anemia and guide clinical care to improve quality of life.
CONDITIONS
Brief Title
Brain Cognitive Network Abnormalities in Anemia Patients Using fNIRS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of anemia
- First hospitalization
- Male or female, aged 18 to 65 years
- Willing and able to comply with the study requirements and provide written informed consent
You will not qualify if you...
- History of psychiatric illness
- History of severe brain disease
- Other reasons deemed unsuitable for inclusion by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Within 48 hours of admission
Participants undergo assessments including cognitive function, anxiety, depression, sleep quality, physical fatigue, appetite condition, and brain oxygenation using functional near-infrared spectroscopy within 48 hours of admission.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Regenerative Medicine Center
Tianjin, Tianjin Municipality, China
Actively Recruiting
Research Team
Z
ZheXiang Kuang, MSN
X
Xiao Yu, Undergraduate
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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