Actively Recruiting

Age: 16Years - 65Years
All Genders
Healthy Volunteers
NCT05085704

Brain Metabolism Observed at 7 Tesla

Led by University of Texas Southwestern Medical Center · Updated on 2023-10-25

20

Participants Needed

1

Research Sites

228 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal is to develop methodology to monitor flux in the citric acid cycle in brain via 13C nuclear magnetic resonance (NMR) spectroscopy at 7 Tesla.

CONDITIONS

Official Title

Brain Metabolism Observed at 7 Tesla

Who Can Participate

Age: 16Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescents and adults with previously documented diagnosis of Glut1 Deficiency confirmed by genetic testing or PET scan
  • Ages 16 to 65 years
  • Persons with dental fillings, dental crowns, or short (max. 4 cm) dental retainer wires are eligible
Not Eligible

You will not qualify if you...

  • Uncontrolled seizure disorder with grand mal seizures in the past 3 months
  • Pregnant females; pregnancy test required for females of childbearing potential
  • Implanted orthopedic metal in bone within radio frequency coil volume unless approved by PI and Medical Director
  • Presence of implanted cardiac devices like ICD or pacemakers, neurostimulators, or similar devices
  • Claustrophobia
  • Presence of questionable ferrous implants, bullets, BBs, or shrapnel
  • Non-fluency in English preventing immediate cooperation during study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UT Southwestern Medical Center

Dallas, Texas, United States, 75390

Actively Recruiting

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Research Team

J

Juan M Pascual, M.D.

CONTACT

A

Adrian Avila, B.S.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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