Actively Recruiting
Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)
Led by Odense University Hospital · Updated on 2026-04-06
860
Participants Needed
1
Research Sites
739 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Calciphylaxis is a rare yet life-threatening condition involving pronounced calcification in small blood vessels of the skin. Knowledge about its underlying mechanisms and contributing risk factors remains limited. Chronic kidney disease is one of the strongest disease predictors. No evidence based effective therapy is currently available. Research on the topic is mainly hindered by the condition's rarity. The study Calciphylaxis in patients with chronic kidney disease - A study of the Danish Calciphylaxis Research Initiative (DanCaRI) is set up to facilitate the systematic retrospective and prospective comparison of patients with chronic kidney disease and calciphylaxis to matched patients with chronic kidney disease who did not develop calciphylaxis thereby providing new knowledge that can support prevention, early detection, and new treatment approaches.
CONDITIONS
Official Title
Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosis of chronic kidney disease (CKD)
- Suspicion or new diagnosis of calciphylaxis (for cases), with diagnosis agreed by involved specialists
- Ability to give informed consent
- Ability to participate in a clinical study as assessed by the local investigator
- Provides written informed consent
- Self-assessed as healthy and confirmed by local investigators (for healthy reference group)
You will not qualify if you...
- Calciphylaxis diagnosis is excluded (for cases)
- Diagnosis of calciphylaxis (for controls)
- For healthy controls up to 60 years old: estimated glomerular filtration rate (eGFR) below 60 ml/min/1.72m2
- For healthy controls over 60 years old: eGFR below the 95% confidence interval adjusted for age according to Danish Society of Nephrology reference ranges
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Odense University Hospital
Odense, Denmark, 5000
Actively Recruiting
Research Team
S
Subagini Nagarajah, PhD
CONTACT
A
Alexandra Scholze, Dr. med., PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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