Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID05651945

Stroke Recovery Program: Cardiac Rehabilitation of Stroke Survivors

Led by Hackensack Meridian Health · Updated on 2026-02-05

150

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

H

Hackensack Meridian Health

Lead Sponsor

T

The Cardiovascular Institute of New Jersey at Rutgers Robert Wood Johnson Medical School

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness of a cardiac rehabilitation program for stroke survivors. The study aims to determine if adding cardiac rehabilitation to the standard care treatments improves recovery of function and reduces hospital readmissions, recurrent strokes, and mortality. The program focuses on patients diagnosed with ischemic or hemorrhagic stroke who are medically cleared for cardiac rehabilitation. Participants are assigned randomly to one of two groups: one group receives a traditional medically supervised cardiac rehabilitation program with 36 sessions of progressive exercise lasting 30 to 50 minutes each, along with educational sessions about cardiovascular disease risk factors. The other group receives standard care therapies such as physical, occupational, or speech therapy as prescribed by their doctors. The cardiac rehab program also includes close monitoring during exercise and possible consultations with rehabilitation psychologists or dieticians based on assessments. During the study, participants undergo various evaluations including walking tests, cognitive assessments, quality of life questionnaires, and measures of physical activity from 30 days to 120 days post-stroke. Researchers will also track hospital readmissions, stroke recurrence, and mortality up to one year after stroke. The study involves ongoing monitoring and assessments to understand the impact of cardiac rehabilitation on stroke recovery over time.

CONDITIONS

Brief Title

Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Diagnosis of ischemic or hemorrhagic stroke confirmed by radiologic evidence
  • Medically cleared by a cardiologist for cardiac rehabilitation with no contraindications per AACVPR guidelines
  • Ability to safely transfer on/off a recumbent bike, with or without assistive devices or help
  • Ability to follow simple commands and communicate pain or distress
  • Admission to an Inpatient Rehabilitation Facility after stroke
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Presence of subarachnoid hemorrhage, intracranial aneurysm, intracranial hemangioma, or arteriovenous malformation
  • Medical conditions that prevent participation as determined by the Principal Investigator
  • Inability to complete baseline assessment within 60 days after stroke diagnosis
  • Considered unable to comply with study requirements
  • Known terminal illness with life expectancy less than 1 year
  • Diagnosis eligible for traditional cardiac rehabilitation covered by insurance
  • Unable to understand or speak English

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Duration of 36 exercise sessions

Participants undergo a cardiac rehabilitation program consisting of 36 outpatient exercise sessions (30-50 minutes each) including educational sessions on cardiovascular disease risk factors. Based on initial assessments, participants may be referred for consultations with a rehabilitation psychologist or dietician as needed. Participants also continue to receive their standard of care therapies as prescribed by their physicians.

36 outpatient sessions

Follow-up

Duration - Up to 1 year post-stroke

Participants are monitored for outcomes including physical function and quality of life up to 1 year post-stroke.

Visits as scheduled for assessments up to 1 year

Trial Site Locations

Total: 1 location

1

Hackensack Meridian Health - JFK Johnson Rehabilitation Institute

Edison, New Jersey, United States, 08820

Actively Recruiting

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Research Team

H

Hayk Petrosyan, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis.

Lindsey Anderson, Neil Oldridge, David R Thompson...

https://pubmed.ncbi.nlm.nih.gov/26764059

Physical activity and exercise recommendations for stroke survivors: a statement for healthcare professionals from the American Heart Association/American Stroke Association.

Sandra A Billinger, Ross Arena, Julie Bernhardt...

https://pubmed.ncbi.nlm.nih.gov/24846875

Impact of a Stroke Recovery Program Integrating Modified Cardiac Rehabilitation on All-Cause Mortality, Cardiovascular Performance and Functional Performance.

Sara J Cuccurullo, Talya K Fleming, William J Kostis...

https://pubmed.ncbi.nlm.nih.gov/31634208

Impact of Modified Cardiac Rehabilitation Within a Stroke Recovery Program on All-Cause Hospital Readmissions.

Sara J Cuccurullo, Talya K Fleming, John B Kostis...

https://pubmed.ncbi.nlm.nih.gov/33657031

Impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community.

Kashish Goel, Ryan J Lennon, R Thomas Tilbury...

https://pubmed.ncbi.nlm.nih.gov/21576654

Aerobic Exercise Recommendations to Optimize Best Practices in Care After Stroke: AEROBICS 2019 Update.

Marilyn MacKay-Lyons, Sandra A Billinger, Janice J Eng...

https://pubmed.ncbi.nlm.nih.gov/31596465