Actively Recruiting
Causes and Outcomes of Febrile Illness in Health Facilities in Rural South and Southeast Asia
Led by University of Oxford · Updated on 2026-01-12
7200
Participants Needed
4
Research Sites
232 weeks
Total Duration
On this page
Sponsors
U
University of Oxford
Lead Sponsor
S
Shoklo Malaria Research Unit (SMRU)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This prospective multi-site observational study aims to describe causes and clinical outcomes of acute febrile illness as well as host biomarkers in patients aged \>28 days residing in rural areas in Laos, Myanmar, Thailand, the Thai-Myanmar border region, and Bangladesh and presenting with acute febrile illnesses (≤ 14 days duration) to participating health facilities. This study is funded by the UK Wellcome Trust. The grant reference number is 215604/Z/19/Z
CONDITIONS
Official Title
Causes and Outcomes of Febrile Illness in Health Facilities in Rural South and Southeast Asia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- The patient or their parent/guardian/caretaker is willing and able to give informed consent or assent for participation
- Patient is older than 28 days (day of birth = Day 1)
- Axillary temperature at presentation is 37.5°C (99.5°F) or higher, or below 35.5°C (95.9°F) with no more likely cause than sepsis for low temperature, or history of fever in the past 24 hours
- Onset of illness is 14 days or less prior to presentation
You will not qualify if you...
- Patient's presentation is due to accident or trauma
- Presentation occurs 3 days or less after routine immunizations
- Patient is currently under follow-up or has been without fever for less than 72 hours after completing a follow-up period
- Treating healthcare worker decides to send the patient home after initial assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Building Resources Across Communities (BRAC)
Dhaka, Bangladesh, 1212
Not Yet Recruiting
2
Laos-Oxford-Mahosot Wellcome Trust Research Unit
Vientiane, Laos, 01000
Actively Recruiting
3
Shoklo Malaria Research Unit
Mae Sot, Changwat Tak, Thailand, 63110
Actively Recruiting
4
Chiangrai Clinical Research Unit (CCRU)
Chiang Rai, Thailand, 57000
Actively Recruiting
Research Team
Y
Yoel Lubell, Prof.
CONTACT
R
Rusheng Chew, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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