Actively Recruiting
Cervical Radiculopathy Imaging Using MR Neurography With Electrodiagnostic Correlation
Led by Hospital for Special Surgery, New York · Updated on 2026-04-27
20
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying patients with cervical radiculopathy, a condition involving nerve issues in the neck area. This observational project aims to assess the diagnostic and prognostic value of magnetic resonance neurography (MRN), electrodiagnostic (EDX) studies, and clinical history and physical exam findings. The study will explore how these data separately or together relate to patient responses to procedural and non-procedural treatments. Participants diagnosed with unilateral cervical radiculopathy and clinical weakness will undergo specialized cervical MRI scans with magnetic resonance neurography sequences to examine nerve roots outside the spinal canal. Electrodiagnostic testing results will also be included if performed prior to surgery. The study focuses on patients with symptom onset between 2 and 12 weeks and MRI findings showing radiculopathy, with or without spinal cord compression. During the study, researchers will collect baseline imaging and electrodiagnostic data, then assess pain levels and neck disability at baseline, 3 months, 6 months, and 12 months. Outcomes measured include nerve abnormalities on MRN imaging and their relationship to electrodiagnostic findings. Participants will be monitored over time to better understand the correlations between diagnostic tools and treatment responses. The study is sponsored by the Hospital for Special Surgery, New York, and runs until October 2026.
CONDITIONS
Brief Title
Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness
- 18-60 years old at the time of evaluation
- Symptom onset of 2 to 12 weeks leading up to baseline visit
- Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis/narrowing) based on standard-of-care cervical spine MRI
- Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery
You will not qualify if you...
- Prior cervical surgery or instrumentation
- Those who have had a prior episode of cervical radiculopathy
- History of peripheral neuropathy or another acute or chronic neurodegenerative condition
- History of stroke, cerebellar disease, or central nervous system disease
- Contraindications to undergoing a standard MRI examination (e.g., pregnancy)
- Patients presenting with bilateral cervical radiculopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Baseline visit
Participants undergo cervical magnetic resonance neurography (MRN) and electrodiagnostic testing to evaluate cervical nerve roots and correlate imaging findings.
1 visit (in-person)
Duration - 12 months
Participants are followed to assess pain and neck disability over time using surveys at multiple timepoints.
Visits at 3 months, 6 months, and 12 months (in-person or remote)
Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Research Team
J
J. Levi Chazen, MD
C
Carlo Milani, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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