Characterization of Biophysical and Mechanical Parameters on the Skin of Subjects With a Diagnosis of Breast Cancer After Surgery and Undergoing Adjuvant Treatment.

What this Trial Is About

Researchers are studying the skin characteristics of patients with breast cancer who are undergoing various adjuvant treatments after surgery. The study focuses on understanding the chemical, physical, and structural changes in the skin to help prevent and manage skin side effects caused by hormone therapy, chemotherapy, and radiotherapy. These skin side effects can affect treatment adherence and outcomes, especially in estrogen receptor positive breast cancer patients receiving Tamoxifen, Aromatase Inhibitors, or Paclitaxel. Participants in this observational study will be grouped based on their treatment: Tamoxifen, Aromatase Inhibitors, or Paclitaxel, with some also receiving radiotherapy. The study involves performing specialized skin tests and using professional instruments to assess skin condition. The tests include questionnaires like the Skindex 29 and instrumental evaluations to monitor skin hydration and other physical properties. During the study, participants will undergo skin assessments and complete quality of life questionnaires related to skin conditions. The primary outcomes measured are forearm skin hydration and the impact of skin disease on quality of life, assessed on a single day. This study aims to provide detailed data on skin changes during breast cancer adjuvant therapy, helping guide future management and development of new dermocosmetic products. The study is set to run until May 2025.

Characterization of Biophysical and Mechanical Parameters on Skin of Breast Cancer Patients