Actively Recruiting

Age: 18Years +
All Genders
ID07345975

Characterization of Opposition to Organ Donation at Strasbourg University Hospital in 2024-2025

Led by University Hospital, Strasbourg, France · Updated on 2026-01-16

100

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In France, there is a significant shortage of organ transplants compared to the number of people waiting, with many patients dying while waiting. The law assumes everyone is a donor unless they have stated otherwise, but family refusals remain high, often due to uncertainty or lack of discussion. This observational study aims to better understand the reasons behind family opposition to organ donation at Strasbourg University Hospital between 2024 and 2025 to help increase donation rates. The study focuses on patients who are brain dead or eligible for organ donation after circulatory arrest, hospitalized or transferable to the Strasbourg University Hospital intensive care unit. Researchers will observe and document family responses during donation discussions coordinated by the hospital's organ procurement team. There are no interventions or treatments involved as this is an observational study. Participants' family members will be engaged in interviews to assess their certainty or uncertainty regarding organ donation decisions. The primary outcome is the distribution of family positions about organ donation over a 12-month period. This study seeks to clarify factors influencing refusal rates to support increased organ donation and transplantation in the future.

CONDITIONS

Brief Title

Characterization of Opposition to Organ Donation at Strasbourg University Hospital in 2024-2025

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who are brain dead and/or eligible for a Maastricht 3 protocol (discontinuation of active treatment with death due to circulatory arrest in intensive care)
  • Hospitalized in the intensive care unit of the Strasbourg University Hospital or transferable to the Strasbourg University Hospital for multi-organ removal (anticipated approach)
  • Existence of relatives with whom discussion is possible
  • Presence of organ procurement coordination at the initial donation interview
Not Eligible

You will not qualify if you...

  • Absence of relatives of the deceased (no interview with them)
  • Absence of organ procurement coordination during the initial discussion with relatives regarding organ and tissue procurement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - Up to 12 months

Participants who undergo routine care are observed regarding their positions on organ donation.

Visits as part of standard hospital care

Trial Site Locations

Total: 1 location

1

Service d'Anesthésie, Réanimation et Médecine Périopératoire - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

C

Charlotte POUSSARDIN, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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