Actively Recruiting
Study of Chest Pain and Hidden Cardiac Amyloidosis in Men Aged 65 and Older Without Coronary Artery Disease
Led by Rigshospitalet, Denmark · Updated on 2026-02-27
300
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are conducting a study to find out how common Cardiac Amyloidosis CA is in men aged 65 and older who have chest pain but no signs of coronary artery disease CAD. This observational, prospective study includes patients who already had a CT coronary angiogram or Rb-PET scan to exclude CAD before joining. Participants will undergo several tests such as blood tests, urine samples, ECG, echocardiography, and bone scintigraphy to check for signs of CA. If needed, an endomyocardial biopsy may be performed to gather more information. This is not a drug trial but an assessment through examinations. During the study, researchers will carefully monitor participants using these tests to measure how often CA occurs in this group of men. The main outcome is to determine the prevalence of ATTR-CA within four weeks. The study is sponsored by Rigshospitalet, Denmark, and participation involves regular evaluations without treatment interventions.
CONDITIONS
Brief Title
CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis
Research Team
N
Navid Noory, MD
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