Actively Recruiting
Clinical Effects of Keratinized Mucosa Augmentation Around Dental Implant With Free Gingival Graft in Different Surgical Timing at Mandibular Posterior Sites
Led by The Dental Hospital of Zhejiang University School of Medicine · Updated on 2025-07-28
24
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare clinical outcomes and tissue stability at dental implant sites in the lower jaw (mandibular posterior region) where there is insufficient buccal keratinized gingiva. It evaluates the use of free gingival grafts applied either before implant surgery or during the second stage of implant surgery to support implant success and tissue health. The study has two groups: one receiving free gingival graft surgery at the same time as the second stage of implant surgery followed by restoration after 6 to 8 weeks, and the other receiving the graft 6 to 8 weeks before implant placement. These two timing approaches for the graft are being assessed to determine their effects on tissue stability and clinical outcomes around the implants. Participants will undergo measurements of the width and thickness of keratinized mucosa before surgery, immediately after, and at 2 and 6 months post-surgery. Additional follow-ups at least 6 months after restoration will assess discomfort, plaque buildup, bleeding on probing, probing depth around the implant, marginal bone loss, and patient satisfaction. This detailed monitoring helps understand the impact of graft timing on implant site health over time.
CONDITIONS
Brief Title
Clinical Effects of Keratinized Mucosa Augmentation Around Dental Implant With Free Gingival Graft in Different Surgical Timing at Mandibular Posterior Sites
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Partially missing teeth in the back lower jaw planned for implant-supported fixed restoration
- Buccal keratinized mucosa width less than 2mm at the implant site, with transplantation area not exceeding 2 teeth
- No prior soft tissue augmentation at the implant site
- Good overall health without systemic diseases affecting bone metabolism or wound healing
- Good periodontal condition with no progressive bone loss or abscess
- Smoking 10 or fewer cigarettes per day
You will not qualify if you...
- Uncontrolled metabolic diseases
- Severe periodontal disease with unstable condition
- Smoking more than 10 cigarettes per day
- Unwilling to participate in follow-up visits
- Other conditions that prevent implant treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 to 8 weeks
Participants receive a free gingival graft surgery 6 to 8 weeks before implant placement to augment keratinized mucosa.
1 surgery visit and follow-up assessments
Duration - 6 to 8 weeks
Participants undergo implant surgery with simultaneous free gingival graft during the second stage of implant surgery, followed by restoration 6 to 8 weeks later.
1 surgery visit and 1 restoration visit
Duration - At least 6 months
Participants are monitored for clinical outcomes including keratinized mucosa width and thickness, postoperative discomfort, and implant health for at least 6 months after restoration.
Several follow-up visits over 6 months
Trial Site Locations
Total: 1 location
1
The Stomatology Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
M
Misi Si
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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