Actively Recruiting

Age: 50Years +
All Genders
NCT06122077

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

Led by Freenome Holdings Inc. · Updated on 2025-08-05

20000

Participants Needed

36

Research Sites

185 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The PROACT LUNG study is a prospective multi-center observational study to validate a blood-based test for the early detection of lung cancer by collecting blood samples from high-risk participants who will undergo a routine, standard-of-care screening Low-Dose Computed Tomography (LDCT).

CONDITIONS

Official Title

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 years or older within 30 days of enrollment
  • Current or former smokers with a cumulative smoking history of 60 20 pack-years
  • Able to understand and willing to sign informed consent and HIPAA authorization documents
Not Eligible

You will not qualify if you...

  • Receiving active cancer treatment such as surgery, chemotherapy, biologic therapy, immunotherapy, or radiation at enrollment
  • History of any cancer within 5 years before enrollment except non-melanoma skin cancer
  • History of organ, tissue, or bone marrow transplant
  • Had lung cancer screening or chest CT scan within 12 months before enrollment
  • Having symptoms of lung cancer including coughing up blood or related syndromes
  • Received a blood transfusion within 30 days before enrollment
  • Known pregnancy
  • Participated or currently participating in another Freenome-sponsored clinical study
  • Participated or currently participating in a clinical trial with experimental medication within 60 days before enrollment
  • Any condition that the Investigator believes should exclude the participant from the study

AI-Screening

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Trial Site Locations

Total: 36 locations

1

Science 37

Los Angeles, California, United States, 90230

Actively Recruiting

2

Stamford Hospital

Stamford, Connecticut, United States, 06902

Actively Recruiting

3

Hillcrest Medical Research

DeLand, Florida, United States, 32720

Actively Recruiting

4

Universal Axon Clinical Research

Doral, Florida, United States, 33166

Actively Recruiting

5

I.H.S Health, LLC

Kissimmee, Florida, United States, 34741

Actively Recruiting

6

United Medical Research

Port Orange, Florida, United States, 32127

Actively Recruiting

7

Charter Research

The Villages, Florida, United States, 32162

Actively Recruiting

8

Charter Research

Winter Park, Florida, United States, 32792

Actively Recruiting

9

SpeciCare, Inc

Gainesville, Georgia, United States, 30501

Actively Recruiting

10

University of Chicago

Chicago, Illinois, United States, 60637

Actively Recruiting

11

Walgreens

Deerfield, Illinois, United States, 60015

Actively Recruiting

12

Springfield Clinic, LLP

Springfield, Illinois, United States, 62702

Actively Recruiting

13

Aton Health

Leawood, Kansas, United States, 66211

Actively Recruiting

14

Ascension Via Christi Wichita

Wichita, Kansas, United States, 67214

Actively Recruiting

15

Ascension St. Agnes Hospital

Baltimore, Maryland, United States, 21237

Actively Recruiting

16

Cape Cod Hospital

Hyannis, Massachusetts, United States, 02601

Actively Recruiting

17

Memorial Hospital at Gulfport

Gulfport, Mississippi, United States, 39503

Actively Recruiting

18

Renown Regional Medical Center

Reno, Nevada, United States, 89502

Actively Recruiting

19

Inspira Medical Center

Mullica Hill, New Jersey, United States, 08062

Actively Recruiting

20

Our Lady of Lourdes Hospital

Binghamton, New York, United States, 13905

Actively Recruiting

21

Wakemed

Raleigh, North Carolina, United States, 27610

Actively Recruiting

22

Altru Health System

Grand Forks, North Dakota, United States, 58201

Actively Recruiting

23

Hightower Clinical

Oklahoma City, Oklahoma, United States, 73102

Actively Recruiting

24

Oregon Health & Science University

Portland, Oregon, United States, 97201

Actively Recruiting

25

Clinical Research Associates of Central PA

DuBois, Pennsylvania, United States, 15801

Actively Recruiting

26

US Digestive Health at Lancaster

Lancaster, Pennsylvania, United States, 17601

Actively Recruiting

27

Temple University

Philadelphia, Pennsylvania, United States, 19140

Actively Recruiting

28

Guthrie Medical Group

Sayre, Pennsylvania, United States, 18840

Actively Recruiting

29

US Digestive Health at Wyomissing

Wyomissing, Pennsylvania, United States, 19610

Actively Recruiting

30

Medical University of South Carolina (MUSC)

Charleston, South Carolina, United States, 29425

Actively Recruiting

31

McLeod Health

Florence, South Carolina, United States, 29506

Actively Recruiting

32

Circle Clinical Research

Pierre, South Dakota, United States, 57104

Actively Recruiting

33

The Jackson Clinic, PA

Jackson, Tennessee, United States, 38305

Actively Recruiting

34

Horizon Clinical Research Group

Houston, Texas, United States, 77008

Actively Recruiting

35

CHRISTUS Trinity Mother Frances Health System

Tyler, Texas, United States, 75701

Actively Recruiting

36

Ascension Columbia St. Mary's Wisconsin

Milwaukee, Wisconsin, United States, 53211

Actively Recruiting

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Research Team

H

Harris Naemi, BS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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