Actively Recruiting

Age: 18Years +
All Genders
ID07001696

Combining Chest X-Ray Findings With Arterial Blood Gas Analysis to Develop a Machine Learning Model Predicting Mechanical Ventilation Need in Critically Ill Patients

Led by Zagazig University · Updated on 2025-06-03

2160

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to develop and validate a machine learning model that combines chest X-ray results with arterial blood gas (ABG) analysis to predict the need for mechanical ventilation in critically ill adult patients. The study is conducted at Zagazig University Hospitals and seeks to improve critical care decisions by integrating radiological and biochemical data using artificial intelligence, comparing the model's predictions against standard clinical assessments. The study plans to enroll about 2,160 critically ill adults over six months. Participants include those clinically assessed to require mechanical ventilation and a control group of age- and sex-matched critically ill patients who do not need ventilation. Data collected include chest X-ray findings and ABG parameters such as pH, PaO2, PaCO2, and HCO3. The machine learning model will be trained on 70% of the data and tested on the remaining 30%, with performance measured by accuracy and error metrics. Participants will undergo evaluation including chest X-rays and ABG tests at the time of assessment. Researchers will collect demographic and clinical information to support model development. The study measures the model's accuracy in predicting ventilation needs within 24 hours of patient presentation. Ethical approval has been obtained, and the study is designed to enhance objective and efficient management of critically ill patients using combined imaging and laboratory data.

CONDITIONS

Brief Title

Combining Chest X-Ray and Arterial Blood Gas Findings to Predict Need for Mechanical Ventilation in Critically Ill Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Critically ill adult patients aged 18 years or older
  • Patients assessed to require mechanical ventilation
  • Age- and sex-matched critically ill patients not requiring mechanical ventilation (control group)
  • Availability of both chest X-ray and arterial blood gas (ABG) analysis at the time of evaluation
Not Eligible

You will not qualify if you...

  • Missing or incomplete data, such as absent chest X-ray or ABG results
  • Chronic lung diseases unrelated to current admission, including COPD and pulmonary fibrosis
  • Pregnant females

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 6 months

Participants undergo chest X-ray and arterial blood gas analysis to collect data for the machine learning model.

1 visit (in-person) at the time of evaluation

Long-term Monitoring

Duration - Up to 6 months

Collected data is used to validate and assess the predictive accuracy of the machine learning model in identifying the need for mechanical ventilation.

No additional visits; data analysis only

Trial Site Locations

Total: 1 location

1

Faculty of medicine, zagazig university

Zagazig, Al Sharqia, Egypt, 44151

Actively Recruiting

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Research Team

O

Omaima Ibrahim Prof

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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