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Phase 3
Age: 18Years - 70Years
All Genders
ID07664592

Comparing the Effectiveness of Three Toothpastes for Fast Relief of Sensitive Teeth in Adults

Led by Colgate Palmolive · Updated on 2026-08-07

132

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating how well three different toothpaste technologies relieve dentin hypersensitivity, a condition causing sharp pain from exposed tooth dentin. The study compares toothpastes containing 8% Arginine, 8% Arginine with Zinc Phosphate, and 5% Calcium Sodium Phosphosilicate CSPS to determine their immediate and short-term effectiveness for adults with sensitive teeth. Participants are randomly assigned to one of three groups, each receiving a specific toothpaste paired with a soft-bristled toothbrush. After initial in-office application and assessment of immediate relief, participants use their assigned toothpaste at home, brushing twice daily for 14 days. Follow-up visits to the clinic occur on days 1, 3, 7, and 14 to assess sensitivity and response. During the study, participants undergo dental exams and complete questionnaires about their sensitivitys impact on quality of life. Sensitivity is measured using stimuli and scales such as the Schiff Cold Sensitivity Scale and a visual analog scale. Researchers track changes from baseline immediately after treatment and throughout the 14-day period to evaluate the toothpastes effects. The study includes safety monitoring and requires participants to avoid certain oral activities before follow-up visits.

CONDITIONS

Brief Title

Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies

Research Team

C

Cassiano K Rosing, PhD

J

Juliano Cavagni, PhD

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