Actively Recruiting

Phase Not Applicable
Age: 20Years - 80Years
All Genders
Healthy Volunteers
ID06011018

Comparison of Effects of Mirror Therapy Combined With Neuromuscular Electrical Stimulation or Binaural Beats on Cortical Excitability, Heart Rate Variability and Lower Limb Motor Function in Stroke Patients

Led by Kaohsiung Medical University Chung-Ho Memorial Hospital · Updated on 2025-09-04

72

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of mirror therapy combined with either neuromuscular electrical stimulation or binaural beat stimulation on improving lower limb motor function in patients who have experienced a stroke. The study also investigates how changes in brain activity relate to motor function recovery after stroke. This research is designed to provide insights into rehabilitation methods for stroke survivors. Participants will receive one of three treatments: mirror therapy alone, mirror therapy with electrical stimulation applied to the affected leg's tibialis anterior muscle, or mirror therapy combined with listening to music featuring 14Hz binaural beat stimulation. Mirror therapy involves seated ankle exercises performed with a mirror placed between the legs, with specific timing for exercise and rest. Electrical stimulation uses a frequency of 35 Hz and pulse width of 250 microseconds. These interventions are compared to determine their effects on motor recovery. During the study, participants' motor function will be assessed using the Fugl-Meyer assessment for the lower extremity as the primary outcome. Additional evaluations include muscle tone measurement, mobility tests, balance assessment, and daily living activities scales. These assessments are brief, ranging from 5 to 10 minutes each, allowing researchers to monitor changes in motor abilities and brain excitability. The study is randomized and single-blind, involving adults aged 20 to 80 years who meet specific criteria related to stroke history and physical abilities.

CONDITIONS

Brief Title

Comparison of Effects of Mirror Therapy Combined With Neuromuscular Electrical Stimulation or Binaural Beats Stimulation on Cortical Excitability, Heart Rate Variability and Lower Limb Motor Function in Patients With Stroke

Who Can Participate

Age: 20Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • First occurrence of stroke at least 6 months ago
  • Mini-mental state examination score 24 or higher
  • Modified Ashworth's scale of ankle muscle 3 or less
  • Ability to sit independently for at least 30 minutes
  • Brunnstrom stage 3 or higher
  • Age between 20 and 80 years
Not Eligible

You will not qualify if you...

  • Speech impairment
  • Hearing impairment
  • Visual impairment
  • Other orthopedic diseases or nerve damage
  • Complete sensory impairment
  • Presence of pacemaker or metal implants

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Participants receive mirror therapy alone or combined with electrical stimulation or binaural beat therapy to improve lower limb motor function after stroke.

Trial Site Locations

Total: 1 location

1

Kaohsiung Medical University, Department of Physical Therapy

Kaohsiung City, Taiwan, 807

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Research Team

L

LIN JAU HONG, Ph.D.

L

LIN YEN YU, Master's degree

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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