Actively Recruiting
Comprehensive Assessment of Neurodegeneration and Dementia
Led by McGill University · Updated on 2026-01-20
1573
Participants Needed
19
Research Sites
704 weeks
Total Duration
On this page
Sponsors
M
McGill University
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are/will be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.
CONDITIONS
Official Title
Comprehensive Assessment of Neurodegeneration and Dementia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Has subjective or objective cognitive impairment
- Written informed consent must be obtained and documented (from the patient or, where jurisdictions allow it, from a caregiver/family member)
- Sufficient proficiency in English or French to undertake self report and neuropsychological testing
- Geographic accessibility to the study site
- Must have a study partner who can participate as required in the protocol (provide corroborative information)
- Up to 12 years of education
- Fits into one of the following groups: Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Vascular Mild Cognitive Impairment, Parkinson's Disease, Parkinson's Disease with Mild Cognitive Impairment
You will not qualify if you...
- Presence of other significant known chronic brain diseases such as moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, serious developmental handicap, malignant tumors, Parkinson's disease (except for the Parkinson's cohort), and other rare brain illnesses
- Ongoing alcohol or drug abuse that may interfere with study compliance
- Symptomatic stroke within the previous year
- Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 19 locations
1
University of Calgary
Calgary, Alberta, Canada, T2N 1N4
Actively Recruiting
2
University of Alberta Hospital
Edmonton, Alberta, Canada, T6G 2B7
Actively Recruiting
3
Djavad Mowafaghian Centre for Brain Health
Vancouver, British Columbia, Canada, V6T 1Z3
Actively Recruiting
4
Island Health
Victoria, British Columbia, Canada, V8R 6R3
Not Yet Recruiting
5
Veteran's Memorial Building
Halifax, Nova Scotia, Canada, B3E 2E1
Actively Recruiting
6
Hamilton General Hospital
Hamilton, Ontario, Canada, L8L 2X2
Actively Recruiting
7
St. Joseph's Health Care London
London, Ontario, Canada, N6A 4V2
Actively Recruiting
8
Gait and Brain Lab
London, Ontario, Canada, N6C 5J1
Actively Recruiting
9
Bruyère Research Institute
Ottawa, Ontario, Canada, K1N 5C8
Active, Not Recruiting
10
Kawartha Centre
Peterborough, Ontario, Canada, K9H 2P4
Active, Not Recruiting
11
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5
Active, Not Recruiting
12
University Health Network Memory Clinic
Toronto, Ontario, Canada, M5T 2S8
Active, Not Recruiting
13
Baycrest Clinical Unit
Toronto, Ontario, Canada, M6A 1W1
Actively Recruiting
14
University of Waterloo
Waterloo, Ontario, Canada, N2L 3G1
Active, Not Recruiting
15
Research Institute of the McGill University Health Centre
Montreal, Quebec, Canada, H3G 1A4
Active, Not Recruiting
16
Jewish General Hospital/McGill Memory Clinic
Montreal, Quebec, Canada, H3T 1E2
Actively Recruiting
17
Clinique de cognition Institut universitaire de gériatrie de Montréal
Montreal, Quebec, Canada, H3W 1W5
Actively Recruiting
18
Hôpital Enfant-Jésus
Québec, Quebec, Canada, G1J 1Z4
Actively Recruiting
19
Centre de recherche sur le vieillissement CIUSSS de l'Estrie-CHUS
Sherbrooke, Quebec, Canada, J1J3H5
Active, Not Recruiting
Research Team
H
Howard Chertkow, MD
CONTACT
R
Randi Pilon
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
8
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here