Study of HPV Self-Screening Compared to Professional Screening for Cervical Cancer Risk in Vulnerable Women Living in Reunion Island

What this Trial Is About

This research aims to evaluate community health actions focused on women aged 30 to 65 who are living in vulnerable situations in the outer areas of Reunion Island. The study is designed to assess the effectiveness of these actions in promoting cervical cancer screening by comparing self-screening methods to those performed by health professionals. The trial focuses on human papillomavirus HPV, a risk factor for anal cancer, in people living with HIV. Participants will engage in small group workshops to raise awareness about cervical cancer screening through discussion groups. Additionally, women who are not up to date with their cervical cancer screening will be offered an HPV self-test using a vaginal swab during an individual consultation. This randomized controlled crossover study compares the acceptability and concordance of self-screening versus professional screening. During the study, researchers will monitor how many women complete cervical cancer screening within three months after the community health intervention. Participants will attend awareness sessions and may perform self-testing. The study will track screening completion rates to measure the impact of the interventions. The trial is expected to run until March 2028, with participants followed for at least three months after intervention.

Concordance and Acceptability of Self-screening Compared to Screening Carried Out by a Health Professional for HPV, a Risk Factor for Anal Cancer, by Swab in People Living With HIV. A Randomized Controlled Crossover Study