Cryotherapy and Robotic Assisted Non Ischemic Nephron Sparing Surgery

What this Trial Is About

This research investigates a new surgical method for patients with kidney tumors who are candidates for partial nephrectomy, a procedure that removes part of the kidney. The study aims to compare the safety and effectiveness of using cryoablation at the tumor site instead of the usual approach that temporarily stops blood flow to the kidney during surgery. This alternative technique could address risks associated with current methods that involve warm ischemia, which can harm the kidney. Participants receive a treatment called Cryoablation Assisted Partial Nephrectomy, guided by ultrasound and using a specialized FDA-approved cryoablation device. During surgery, cryoprobes are placed near the tumor margins to freeze the tumor boundary in one cycle lasting five minutes. After freezing, the tumor is removed, and the kidney is repaired while the tissue thaws naturally. This approach avoids the need for interrupting blood flow to the kidney. Throughout the study, participants will be monitored for up to ten years to assess outcomes such as cancer recurrence, the need for additional local treatments, development or worsening of chronic kidney disease, spread of cancer, and overall survival. Researchers will collect data from regular follow-ups to evaluate the long-term safety and success of this cryoablation-assisted technique compared to traditional methods.

Cryaoablation Assisted Partial Nephrectomy a Non Ischemic Approach