Actively Recruiting

Age: 18Years +
All Genders
NCT06535113

Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia

Led by Ciceri Fabio · Updated on 2025-05-08

80

Participants Needed

2

Research Sites

79 weeks

Total Duration

On this page

Sponsors

C

Ciceri Fabio

Lead Sponsor

A

Azienda Ospedaliera Bianchi-Melacrino-Morelli

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study is designed as a collection of biological samples of newly diagnosed acute myeloid leukemia (AML) patients treated in the clinical units involved. Samples of peripheral blood (PB) and bone marrow (BM) will be analyzed to determine the Inflammasome profile before and after a first-line chemotherapy treatment.

CONDITIONS

Official Title

Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Any gender
  • Adults over 18 years old
  • Newly suspected diagnosis of acute myeloid leukemia based on ELN2022 criteria
  • Able to understand the study and consent form
  • Willing to sign the informed consent form
  • For retrospective participants: biological samples collected from adults diagnosed with acute myeloid leukemia between 06/01/2006 and 06/01/2024 according to ELN2017 criteria
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years old
  • Patients unable or unwilling to sign the informed consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

GOM Bianchi Melacrino Morelli

Reggio Calabria, Calabria, Italy, 89133

Actively Recruiting

2

IRCCS Ospedale San Raffaele

Milan, Milan, Italy, 20132

Actively Recruiting

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Research Team

S

Sara Mastaglio, Haematologist MD

CONTACT

V

Vincenzo Mercurio, Ph.D Trial Office Coordinator

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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